Rejuvenescence -リジュベネッセンス-

Furusuto Island where season anomalies exist. These anomalies are believed to be confrontation of two goddesses with silver and golden eyes, so people with such eye colors are worshiped here. At birth of such person mother always dies, and child lives a short life. Yamaki Subaru is current reincarnation of goddess, and this is her story.

[From vndbreview]